Cheap Generic Neurontin (Gabapentin) – From Indications to Reviews

What is Neurontin?

Neurontin is a medication that contains the active ingredient gabapentin. It belongs to the class of drugs known as anticonvulsants or antiepileptic drugs. It is primarily used for the treatment of epilepsy, specifically partial seizures, in adults and children aged 3 years and older. It helps to prevent and control seizures by reducing abnormal electrical activity in the brain.

In addition to its anticonvulsant properties, Neurontin is also prescribed for the management of neuropathic pain. Neuropathic pain is a type of chronic pain that occurs due to damage or dysfunction in the nerves. Conditions such as diabetic neuropathy, postherpetic neuralgia (pain following shingles), and peripheral neuropathy can be effectively treated with this drug.

It works by affecting certain neurotransmitters and ion channels in the central nervous system, helping to reduce the transmission of pain signals and alleviate discomfort associated with neuropathic pain.


Neurontin (gabapentin) is classified as an anticonvulsant or antiepileptic drug. Anticonvulsants are a class of medications primarily used to treat seizures and epilepsy, although they can also have other therapeutic applications. Neurontin’s classification as an anticonvulsant reflects its primary indication for the treatment of partial seizures in adults and children aged 3 years and older.

While this classification is rooted in its anticonvulsant properties, it also has broader applications beyond epilepsy. This drug is commonly prescribed for the management of neuropathic pain, which is pain caused by damage or dysfunction of nerves. It is effective in conditions such as diabetic neuropathy, postherpetic neuralgia (pain following shingles), and peripheral neuropathy.

Furthermore, Neurontin may be used off-label for various conditions, including restless legs syndrome (RLS), fibromyalgia, and migraine prevention. Off-label use refers to the use of a medication for an indication that has not been specifically approved by regulatory authorities but is supported by medical literature and clinical experience.

The classification of this medication as an anticonvulsant underscores its mechanism of action. It works by modulating the activity of certain neurotransmitters and ion channels in the central nervous system, thereby reducing abnormal electrical activity and dampening excessive signaling that can lead to seizures or nerve-related pain.

What is Neurontin generic name?

The generic name for the medication Neurontin is gabapentin. Gabapentin is the active ingredient in Neurontin and is the name used to identify the drug in its unbranded, generic form.

Gabapentin belongs to a class of medications called anticonvulsants or antiepileptic drugs. It works by affecting certain chemicals in the brain and nerves, helping to reduce abnormal electrical activity and alleviate seizures or nerve-related pain.

Generic medications like gabapentin are bioequivalent to their brand-name counterparts. This means that they contain the same active ingredient and are expected to have the same efficacy and safety profiles when used as prescribed.

Gabapentin is available in various dosage forms, including capsules, tablets, and oral solutions, allowing for flexibility in dosing based on individual needs and treatment requirements. The specific dosage form and strength of gabapentin may vary depending on the manufacturer and country.

What is Neurontin used for?

Neurontin is a medication that is used to treat various medical conditions, primarily those related to the central nervous system. Some of the diseases and conditions that this drug is commonly prescribed for include:

  1. Epilepsy: It is an anticonvulsant medication and is approved for the treatment of partial seizures in adults and children aged 3 years and older.
  2. Neuropathic Pain: Neurontin is widely used for the management of neuropathic pain, which is pain caused by damage or dysfunction of nerves. It is commonly prescribed for conditions such as diabetic neuropathy, postherpetic neuralgia (pain following shingles), and peripheral neuropathy.
  3. Restless Legs Syndrome (RLS): It is sometimes prescribed off-label for the treatment of restless legs syndrome, a neurological disorder characterized by an irresistible urge to move the legs, particularly during periods of rest or sleep.
  4. Fibromyalgia: Neurontin may be used off-label as an adjunctive treatment for fibromyalgia, a chronic condition characterized by widespread pain, fatigue, and other symptoms.
  5. Migraine Prevention: Neurontin is sometimes used off-label as a preventive medication for migraines, helping to reduce the frequency and severity of migraine headaches.
  6. Off-label Uses: Neurontin may be prescribed off-label for other conditions such as anxiety disorders, bipolar disorder, social phobia, and alcohol withdrawal symptoms. However, the evidence supporting its efficacy for these uses may vary.

How does Neurontin work?

The precise mechanism of action of gabapentin is not fully understood, but it is believed to involve multiple mechanisms that contribute to its therapeutic effects. Neurontin primarily exerts its pharmacological effects by interacting with certain receptors and channels in the central nervous system. Here are some of the proposed mechanisms of action:

  1. Modulation of Calcium Channels: Neurontin is thought to bind to specific sites on voltage-gated calcium channels in the brain, particularly the α2δ subunit. By binding to these channels, Neurontin inhibits the release of certain excitatory neurotransmitters, such as glutamate, which may contribute to its anticonvulsant and analgesic effects.
  2. GABAergic System Modulation: This drug has been found to increase the synthesis and release of gamma-aminobutyric acid (GABA), a neurotransmitter that has inhibitory effects in the brain. By enhancing GABAergic activity, it may help to reduce neuronal excitability and dampen excessive signaling, which can be beneficial in conditions such as epilepsy and neuropathic pain.
  3. Glutamate Release Inhibition: It has also been found to inhibit the release of the excitatory neurotransmitter glutamate. By reducing glutamate release, Neurontin may further contribute to its anticonvulsant and analgesic properties.

How long does it take Neurontin to work?

The time it takes for Neurontin (gabapentin) to start working can vary from person to person and depends on several factors. Neurontin is an anticonvulsant and neuropathic pain medication that works by affecting certain chemicals in the brain and nerves.

In some individuals, this drug may provide noticeable relief within a few days of starting treatment. However, it’s important to keep in mind that Neurontin’s full therapeutic effects may take several weeks to develop. During this time, the medication gradually builds up in the body, reaching therapeutic levels that can effectively address the symptoms it is prescribed for.

How long does Neurontin stay in your system?

The duration of time that Neurontin (gabapentin) remains in the body can vary based on several factors, including individual metabolism, dosage, and frequency of administration. Generally, it takes approximately 1 to 2 days for Neurontin to be eliminated from the body after discontinuation. However, it’s important to note that trace amounts of the medication may still be detectable in the system for a longer period.

The half-life of this drug is about 5 to 7 hours in individuals with normal kidney function. This means that it takes around 5 to 7 hours for the concentration of Neurontin in the body to decrease by half. After several half-lives, the medication is effectively cleared from the system.

What is the dosage?

The dosage of Neurontin (gabapentin) can vary depending on the condition being treated and individual factors. It’s important to note that dosages should be determined by a healthcare professional based on factors such as the patient’s medical history, the condition being treated, and their response to the medication. The following dosage information provides a general guideline:

For Epilepsy:

  • Adults and adolescents (12 years and older): The starting dose is typically 300 to 900 milligrams (mg) per day, divided into three doses. The dose may be gradually increased every 3 to 7 days based on response and tolerability. The maintenance dose ranges from 900 to 1800 mg per day, divided into three doses. Some individuals may require higher doses, up to a maximum of 2400 to 3600 mg per day.

For Postherpetic Neuralgia (PHN):

  • Adults: The starting dose is typically 300 mg on day one, 300 mg twice daily on day two, and 300 mg three times daily on day three. The dose may be titrated up to a maximum of 1800 to 3600 mg per day, divided into three doses.

For Restless Legs Syndrome (RLS):

  • Adults: The starting dose is typically 300 mg in the evening. The dose may be titrated up to a maximum of 1200 to 2400 mg per day, divided into three doses.


It is possible to overdose on Neurontin (gabapentin) if it is taken in excessive amounts. Taking more than the prescribed dose or intentionally misusing Neurontin can increase the risk of an overdose. Overdosing on Neurontin can have serious consequences and may require immediate medical attention.

Symptoms of an overdose may include:

  1. Drowsiness or extreme sedation;
  2. Slurred speech;
  3. Impaired coordination or balance;
  4. Increased heart rate;
  5. Breathing difficulties, including shallow or labored breathing;
  6. Seizures or convulsions;
  7. Loss of consciousness or coma (in severe cases).

What are contraindications?

Neurontin (gabapentin) may have strict contraindications or situations in which its use is strongly advised against due to the potential risks involved. Here are some examples of strict contraindications:

  1. Hypersensitivity or Allergy: Individuals who have a known hypersensitivity or allergy to gabapentin or any of the components in Neurontin should not use the medication.
  2. Renal Impairment: Neurontin is primarily eliminated from the body through the kidneys. Therefore, individuals with severe renal impairment (kidney dysfunction) may require dosage adjustments or should avoid using Neurontin altogether. Consultation with a healthcare provider is crucial to determine the appropriate course of action.

Additionally, it may have specific precautions and warnings in certain populations or medical conditions, such as:

  1. Pregnancy and breastfeeding: It should be used during pregnancy or breastfeeding only if the potential benefits outweigh the potential risks. It is important to discuss this with a healthcare provider.
  2. Geriatric population: Older adults may require dose adjustments due to age-related changes in kidney function and may be more susceptible to certain side effects, such as dizziness or drowsiness.
  3. Mental health conditions: Neurontin has been associated with an increased risk of suicidal thoughts or behavior. Therefore, close monitoring is necessary in individuals with a history of mental health disorders.
  4. Drug dependence or substance abuse history: Neurontin does not have significant potential for abuse or dependence. However, individuals with a history of drug dependence or substance abuse should be closely monitored while undergoing the therapy.

What are the side effects?

Common side effects (occurring in 1% or more of patients):

  1. Drowsiness or fatigue: Many people experience drowsiness, fatigue, or sedation while taking Neurontin.
  2. Dizziness: Feeling dizzy or lightheaded is a commonly reported side effect.
  3. Peripheral edema: Swelling in the hands, legs, or feet, known as peripheral edema, can occur.
  4. Ataxia: Some individuals may experience impaired coordination or difficulty with balance (ataxia).
  5. Tremor: Shaking or tremors, especially in the hands, may occur.
  6. Nausea and vomiting: Gastrointestinal symptoms such as nausea and vomiting can be seen.
  7. Weight gain: Weight gain is a possible side effect, although the extent and significance can vary.
  8. Blurred vision: Some people may experience temporary blurred or double vision.

Uncommon side effects (occurring in less than 1% of patients):

  1. Allergic reactions: Rarely, Neurontin can cause allergic reactions, including skin rash, itching, swelling, or difficulty breathing. Seek medical attention if these symptoms occur.
  2. Mood changes: Uncommonly, Neurontin may cause mood changes such as irritability, agitation, or depression.
  3. Suicidal thoughts: In rare cases, it has been associated with an increased risk of suicidal thoughts or behavior. It is important to promptly report any changes in mood or suicidal ideation to a healthcare provider.
  4. Changes in blood counts: Neurontin may rarely affect blood cell counts, leading to symptoms like fever, sore throat, or unusual bleeding or bruising.
  5. Respiratory problems: In rare instances, it can cause respiratory issues such as shortness of breath or wheezing.
  6. Liver problems: Although uncommon, Neurontin may rarely cause liver function abnormalities.

What are drug interactions?

Neurontin (gabapentin) can potentially interact with certain medications, and it’s important to discuss all the medications you are taking with your healthcare provider to minimize the risk of drug interactions. Here are some notable drug interactions:

  1. Central Nervous System (CNS) Depressants: Combining Neurontin with other CNS depressants, such as opioids, benzodiazepines, or alcohol, can increase the risk of excessive sedation, respiratory depression, and impaired motor function. Caution and dosage adjustments may be necessary when using Neurontin alongside these medications.
  2. Antacids: Some antacids containing aluminum or magnesium hydroxide may reduce the absorption of gabapentin, potentially decreasing its effectiveness. It is generally recommended to separate the administration of gabapentin and antacids by at least 2 hours.
  3. Opioids: Neurontin may enhance the effects of opioids, including the risk of respiratory depression. Close monitoring is advised when using this drug in combination with opioids.
  4. Diuretics: Thiazide diuretics (e.g., hydrochlorothiazide) can decrease the renal clearance of gabapentin, potentially leading to increased levels of Neurontin in the body. Adjustments to Neurontin dosage may be required in these cases.
  5. Naproxen: Concurrent use of Neurontin and naproxen (a nonsteroidal anti-inflammatory drug) may increase the risk of kidney-related side effects, such as decreased kidney function. Regular monitoring of kidney function is recommended if these medications are used together.

What are withdrawal symptoms?

Discontinuing or abruptly stopping the use of Neurontin can potentially lead to withdrawal symptoms in some individuals. It’s important to follow the guidance of your healthcare provider when discontinuing any medication, including the described one, to minimize the risk of withdrawal effects.

Withdrawal symptoms associated with this drug may include:

  1. Anxiety: Some individuals may experience heightened feelings of anxiety when discontinuing this medication.
  2. Insomnia: Difficulty sleeping or insomnia can occur during the withdrawal period.
  3. Nausea and vomiting: Some people may experience gastrointestinal symptoms like nausea and vomiting upon discontinuation.
  4. Sweating: Increased sweating or excessive perspiration might be observed during the withdrawal process.
  5. Restlessness: Restlessness or agitation can occur as a withdrawal symptom.
  6. Seizures (rare): It is often prescribed to prevent seizures, so abruptly stopping the medication can, in rare cases, trigger seizures.

Gabapentin vs Neurontin

The term “Neurontin” refers to a brand-name medication, while “gabapentin” refers to the generic name of the active ingredient found in Neurontin. Therefore, Neurontin and gabapentin are essentially the same drug, but they may have some similarities and differences worth considering:


  1. Active Ingredient: Both Neurontin and gabapentin contain the same active ingredient, which is gabapentin. This means that they exert the same therapeutic effects and are used to treat similar conditions.


  1. Brand vs. Generic: Neurontin is a brand-name medication that was originally developed and marketed by Pfizer. On the other hand, gabapentin is the generic version of Neurontin, produced by various pharmaceutical companies after the patent for Neurontin expired. The main difference lies in the manufacturer, packaging, and pricing.
  2. Pricing: Neurontin is typically more expensive than generic gabapentin due to factors such as research and development costs, marketing expenses, and brand recognition. Generic gabapentin is usually more affordable, as it doesn’t carry the same brand-related expenses.
  3. Availability: As a brand-name medication, it may be more widely recognized and stocked by pharmacies. Generic gabapentin is also widely available, but different generic manufacturers may produce it under various brand names.

Neurontin pricing

Branded Neurontin:

  • In the early years after its introduction, branded Neurontin was relatively expensive, with average prices ranging from $300 to $400 for a 90-day supply (based on a dosage of 300mg capsules).
  • As the patent expiration approached, the price of branded Neurontin began to decline, but it remained higher than the generic alternatives.

Generic Gabapentin (Neurontin):

  • After the patent for Neurontin expired in 2004, several manufacturers started producing generic versions of gabapentin.
  • The entry of generic gabapentin into the market led to a significant drop in pricing, with average prices ranging from $15 to $50 for a 90-day supply of 300mg capsules.
  • The competition among different manufacturers contributed to further price reductions over time.


Q: Why is Neurontin a controlled substance?

A: No, Neurontin (gabapentin) is not classified as a narcotic. It is an anticonvulsant medication that is primarily used to treat epilepsy and neuropathic pain. It works by affecting certain neurotransmitters in the brain to help control seizures and alleviate pain.

Narcotics, also known as opioids, are a class of drugs that act on the opioid receptors in the brain and are primarily used for pain relief. Examples of narcotics include medications like morphine, oxycodone, and hydrocodone. It works through a different mechanism of action and does not belong to the narcotic class.

Q: Neurontin for dogs – yes or no?

A: Yes, Neurontin (gabapentin) is sometimes prescribed for dogs to manage certain conditions, particularly chronic pain and seizures. It can be used off-label as a veterinary medication.

In dogs, it is often prescribed to help manage chronic pain associated with conditions like arthritis, nerve damage, or musculoskeletal disorders. It can provide relief by reducing the sensation of pain and improving the dog’s overall quality of life.

It is also utilized as an anticonvulsant in dogs to help control seizures. It can be an effective treatment option for dogs with epilepsy or other seizure disorders.

Q: Is neurontin a good painkiller?

A: Neurontin (gabapentin) is commonly used as an adjunctive medication for the management of certain types of pain. While it is not classified as a traditional opioid painkiller, it is known to have analgesic properties and can be effective in relieving certain types of pain.

This drug is particularly prescribed for neuropathic pain, which is pain caused by damage or dysfunction of the nerves. It is often used to treat conditions such as postherpetic neuralgia (pain that occurs after a bout of shingles), diabetic neuropathy (nerve damage due to diabetes), and peripheral neuropathy.

Q: Does neurontin make you sleepy?

A: Yes, one of the common side effects of Neurontin (gabapentin) is drowsiness or sleepiness. Many individuals report feeling more tired or sleepy while taking this drug, especially when they first start using the medication or when the dosage is increased. This sedative effect can be more pronounced in some people than others.

The drowsiness caused by this drug can impact daily activities, including concentration, alertness, and coordination. It is advisable to exercise caution when driving, operating heavy machinery, or engaging in activities that require mental or physical acuity until you know how Neurontin affects you personally.

Q: Neurontin and alcohol

A: It is generally not recommended to combine Neurontin (gabapentin) with alcohol. Both Neurontin and alcohol can have central nervous system depressant effects, which means they can slow down brain activity and impair cognitive and motor functions. When used together, the effects of both substances can be potentiated, leading to increased drowsiness, dizziness, coordination difficulties, and impaired judgment.

Moreover, Neurontin can also enhance the sedative effects of alcohol, potentially increasing the risk of accidents or falls. Additionally, alcohol can interfere with the effectiveness of this drug in treating certain conditions, such as seizures or nerve pain.

Q: Does neurontin cause weight gain?

A: Yes, weight gain is a possible side effect associated with Neurontin (generic name: gabapentin). While not everyone experiences weight gain while taking this medical option, some individuals may notice an increase in body weight. The exact mechanism behind this side effect is not fully understood, but it is believed to be related to changes in appetite and metabolism.

Neurontin reviews

Mark Thompson – *****
Neurontin has been a game-changer for me. I’ve struggled with chronic nerve pain for years, and this medication has provided significant relief. I can finally sleep through the night without the burning sensation in my legs. Highly recommended!

Sarah Johnson – **
I had high hopes for Neurontin, but unfortunately, it didn’t work well for my condition. I suffer from migraines, and while it did slightly reduce the intensity, the side effects were too much to handle. I experienced dizziness and drowsiness, which impacted my daily activities.

James Martinez – ****
Neurontin has been a real lifesaver for my wife. She suffers from postherpetic neuralgia, and this medication has significantly reduced her pain levels. It took some time to find the right dosage, but once we did, the improvement was remarkable. She’s now able to enjoy her daily activities more comfortably.

Emily Collins – ***
I’ve been taking Neurontin for my anxiety disorder, and it has helped calm my racing thoughts. However, the sedative effect is quite strong, and I often feel groggy during the day. It’s a trade-off between anxiety relief and daytime drowsiness.

Michael Anderson – *****
Neurontin has been a godsend for my epilepsy. Since starting this medication, my seizure frequency has significantly decreased. I still experience mild side effects like dizziness and coordination issues, but they’re a small price to pay for the improved control over my condition.

Olivia Peterson – ***
I was prescribed Neurontin for my fibromyalgia pain, but unfortunately, it didn’t provide the relief I was hoping for. I didn’t experience any significant change in my symptoms, and the side effects, such as fatigue and confusion, made it difficult to continue taking the medication.

Benjamin Thompson – ****
Neurontin has been effective in managing my restless leg syndrome (RLS). It helps alleviate the uncomfortable sensations and allows me to have a more peaceful sleep. The only downside is that it takes some time to kick in, so I have to plan my dosage accordingly. Overall, a good option for RLS.

Disclaimer: It is important to consult with a healthcare provider before using this product or any medication to ensure that it is safe and appropriate for you. This info is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition or medication.

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